Publications

Juanico IY, Stockinger AW, Virgen AK, Srisrimal N, Campos SE, Juliano CE (2025). Sustained ERK signaling couples the injury response to organizer formation during Hydra head regeneration. bioRxiv preprint DOI: https://doi.org/10.64898/2025.12.27.696609

 

Cox BD, Mah J, Perez A, and Juliano CE (2025). Extracellular matrix remodeling supports Hydra vulgaris head regeneration and stem cell invasion. bioRxiv preprint DOI: https://doi.org/10.1101/2025.11.07.687297

 

Campos SE, Naziri S, Crane J, Tsverov J, Cox BD, Ciampa C, Spencer RB, Steele RE, Martinez DE and Juliano CE (2025). Wnt signaling restores evolutionary loss of robust foot regeneration rates in Hydra. Nature Communication Dec 10;16(1):11447

 

Little HM, Primack AS, Tsverov J, Nunneley MP, Muhlbauer S, Cox BD, Busse C, Schneid S, Louwagie A, Cazet JF, David CN, Farrell JA, Juliano CE (2025). A Molecular, Spatial, and Regulatory Atlas of the Hydra vulgaris Nervous System. Development 152 (20): dev204983.

 

Wilcox XE, Zhang H, Mah JL, Cazet JF, Mozumder S, Venkatesh S, Juliano CE, Beal PA, Fisher AJ (2025) Phylogenetic and structural analysis of Hydra ADAR. Arch Biochem Biophys. May 2025 DOI: 10.1016/j.abb.2025.110353

 

Escobar A, Kim S, Primack AS, Duret G, Juliano CE, and Robinson JT (2024). Terminal differentiation precedes functional circuit integration in the peduncle neurons in regenerating Hydra vulgaris. Neural Development; October 4, 2024 DOI: 10.1186/s13064-024-00194-2

 

Cazet JF, Siebert S, Morris Little H, Bertemes P, Primack AS, Ladurner P, Achrainer M, Fredriksen MT, Moreland RT, Singh S, Zhang S, Wolfsberg TG, Schnitzler CE, Baxevanis AD, Simakov O, Hobmeyer B, and Juliano CE (2023). A chromosome-scale epigenetic map of the Hydra genome reveals conserved regulators of cell state. Genome Research February 2023. Cover Story. bioRxiv preprint: 10.1101/2022.06.21.496857

 

Liu Y, Kossack ME, McFaul ME, Christensen L, Siebert S, Wyatt SR, Kamei C, Horst S, Arroyo N, Drummond I, Juliano CE, Draper BW (2022). Single-cell transcriptome reveals insights into the development and function of the zebrafish ovary. eLife 2022 May 19 DOI: 10.7554/eLife.76014

 

Badhiwala KN, Primack AS, Juliano CE, Robinson JT (2021). Multiple nerve rings coordinate Hydra mechanosensory behavior. eLife July 30 2021. doi: 10.7554/eLife.64108. doi: bioRxiv preprint: 10.1101/2020.10.16.343384

 

Moneer J, Siebert S, Krebs S, Cazet J, Prexl A, Pan Q, Juliano C, Böttger A (2021) Differential gene regulation in DAPT-treated Hydra reveals candidate direct notch signalling targets. Journal of Cell Science June 14 2021. doi: 10.1242/jcs.258768

 

Cazet JF, Cho A, Juliano CE (2021) Generic injuries are sufficient to induce ectopic Wnt organizers in Hydra. eLife March 29 2021. doi: 10.7554/eLife.60562. bioRxiv preprint: 10.1101/2020.07.06.189811

 

Davies AE, Gillies TE, Siebert S, Pargett M, Tobin SJ, Ram AR, Juliano CE, Quon G, Bissell MJ, Albeck JG (2020). Systems-level properties of EGFR-Ras-ERK signalling amplify local signals to generate dynamic gene expression heterogeneity. Cell Systems 11, 1-15; bioRxiv preprint: doi:10.1101/466656

 

Teefy BB, Siebert S, Cazet JF, Lin H, Juliano CE (2020). PIWI-piRNA pathway-mediated transposable element repression in Hydra somatic stem cells. RNA May 2020 26:550-563. doi: 10.1261/rna.072835.119. bioRxiv preprint: doi:10.1101/731695

 

He S, Grasis JA, Nicotra ML, Juliano CE, Schnitzler CE (2019). Cnidofest 2018: the future is bright for cnidarian research. Evo Devo. 10(20). doi: 10.1186/s13227-019-0134-5

 

Siebert S, Farrell JA, Cazet JF, Abeykoon Y, Primack AS, Schnitzler CE, Juliano CE (2019). Stem cell differentiation trajectories in Hydra resolved at single-cell resolution. Science 365, eaav9314. doi: 10.1126/science.aav9314. bioRxiv preprint: doi:10.1101/460154

 

• Trends in Genetics – Many ways to build a polyp
• Science Perspective – The cells of regeneration
• Nature Methods Research Highlight – Looking at Hydra cells one at a time
• ScienceNews
• The Scientist – Image of the day
• UCD College of biological sciences – News

 

Turco GM, Rodriguez-Medina J, Siebert S, Han D, Vahldick H, Shulse CN, Cole BJ, Juliano CE, Dickel DE, Savageau MA, Brady SM (2019). Molecular Mechanisms Driving Bistable Switch Behavior in Xylem Cell Differentiation. Cell Reports 28, 342–351. doi:10.1016/j.celrep.2019.06.041. bioRxiv preprint: doi:10.1101/543983

 

Rentzsch F, Juliano CE, Galliot B (2019). Modern genomic tools reveal the structural and cellular diversity of cnidarian nervous systems. Curr Opin Neurobiol. 4;56:87-96. doi: 10.1016/j.conb.2018.12.004

 

Dupre C, Grasis JA, Steele RE, Schnitzler CE, Juliano CE (2017). Hydroidfest 2016: Celebrating a renaissance in hydrozoan research. Evo Devo. 8(7). doi: 10.1186/s13227-017-0070-1

 

Siebert S and Juliano CE (2017). Sex, polyps, and medusae: Determination and maintenance of sex in cnidarians. Mol Reprod Dev. 4:105–119.

 

Juliano CE and Hobmayer B (2016). Meeting report on “Animal Evolution: New Perspectives From Early Emerging Metazoans,” Tutzing, September 14-17, 2015. Bioessays. 2016 Mar;38(3):216-9.

 

Juliano CE, Lin H, and Steele RE (2014). Generation of transgenic Hydra by embryo microinjection. J Vis Exp. 2014 Sep 11;(91):51888.

 

Juliano CE, Reich A, Liu N, Götzfried J, Zhong M, Uman S, Reenan RA, Wessel GM, Steele RE, and Lin H (2014). PIWI Proteins and PIWI-interacting RNAs function in Hydra somatic stem cells. Proc Natl Acad Sci. 111(1):337-41. PMCID: 24367095

 

Mani SR and Juliano CE (2013). Untangling the web: the diverse functions of the PIWI/piRNA pathway. Mol Reprod Dev. 80(8):632-64. PMCID: PMC4234069

 

Juliano C, Wang J, and Lin H (2011). Uniting germline and stem cells: The function of Piwi proteins and the piRNA pathway in diverse organisms. Annu Rev Genet. Volume 45. PMCID: PMC3832951

 

Juliano CE, Swartz SZ, and Wessel GM (2010). A conserved germline multipotency program. Development. 137(24):4113-26. PMCID: PMC2990204

 

Juliano C and Wessel GM (2010). Versatile germline genes. Science. 329(5992):640-1.

 

Juliano CE, Yajima M, and Wessel GM (2010). Nanos is required to maintain multipotency in the small micromere lineage of the sea urchin embryo. Dev Biol. 337(2):220-32. PMCID: PMC2812692

 

Juliano CE, and Wessel GM (2009). An evolutionary transition of vasa regulation in echinoderms. Evolution and Development 11:5, 560-573. PMCID: PMC3034130

 

Juliano CE, Voronina E, Stack C, Aldrich M, Cameron AR, Wessel GM. (2006). Germ line determinants are not localized early in sea urchin development, but do accumulate in the small micromere lineage. Dev Biol. 300:406-15.